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Program

12.00 – 13.00	Lunch
13.00 – 13.05	PNB steering committee	Opening remarks
13.05 – 13.15	Laure Elens Erwin Dreesen	Master of Pharmacometrics

Part 1: Pharmacometrics in personalized treatment and therapies

13.15 – 13.45	Sebastiaan Sassen (ErasmusMC)	Towards model-informed precision dosing in clinical care
13.45 – 14.05	Laure Elens (UCLouvain)	Bridging Population PK modeling and experimental models: a pathway to novel biomarkers and clinical insights
14.05 – 14.25	Shannon van der Zeeuw (ErasmusMC)	Personalised dosing of PCSK9-antibodies evolocumab and alirocumab: an in silico study
14.25 – 14.45	Bram Agema (ErasmusMC)	Implementation of model-informed precision dosing for tamoxifen therapy in patients with breast cancer
14.45 – 15.45	Coffeebreak + recycle your poster

Part 2: Pharmacometric research from early career scientists

15:45 – 16:00	Justine Henriot (SCK CEN/KULeuven)	A Generic Preclinical Model for DOTA-TATE-Based TRT: Physiologically-Based Pharmacokinetic Insights into ¹⁶¹Tb-DOTA-TATE and ¹⁷⁷Lu-DOTA-TATE
16:00 – 16.15	Flavie Audy (Pharmalex)	Modeling Targeted Radionuclide Therapy: General Approach to Optimize Dose Selection
16.15 – 16.30	Sebastian Tandar (Leiden University)	Computational Framework for Multi-Objective Optimization of Population Dosing Regimens: A Case Study on Colistin-Amikacin Combination Therapy
16.30 – 16.45	Massinissa Beldjenna (Leiden University)	Beyond averages: Why capturing cellular variability matters in viral dynamic modeling
16.45 – 17.00	Xuanlin Liu (Leiden University)	Mechanistic viral dynamic modeling of in vitro cytomegalovirus infection based on the amount of viral DNA and viral titer

Recycle-your-poster session

During the coffee break we are organizing a recycle-your-poster session: we invite early carreer scientists in our field (MSc, PhD students and Post Docs) to bring a poster as a way to present themselves and their work to (future) colleagues and employers. It does not have to be a new poster, recycled posters on any Pharmacometrics topic serve equally well as a conversation starter and gives other participants a glimpse of the type of work your are doing. No need to submit an abstract, just indicate during registration if you are planning to bring a poster.

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Call for abstracts

The deadline for oral abstract submission is Sunday March 30, 2025. Abstracts (approx. 300 words) should be send to oliver@pharmacometricsnetworkbenelux.org.

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Registration

The meeting will include a light lunch, coffee/tea break and drinks. There is no registration fee, but registration is required for participation. The deadline for registration is Sunday April 13^th 2025.