Incubator Darwin, Niel, Belgium on Thursday May 9th, 2019

Program – Applied PKPD modelling: from prediction to prescription

12:00-13:00       Arrival and lunch

13:00-14:00       Keynote by Ruben Faelens (KU Leuven)

Therapeutic Drug Management: an identification or control task?

14:00-14:30       Sebastian Wicha (University of Hamburg)

Opportunities and challenges for implementation of TDM from a pharmacometric perspective.   

14:30-14:50       Stijn van Beek (Radboud University Medical Centre, Nijmegen)

Population Pharmacokinetics and Model-Informed Precision Dosing of Isoniazid in Tuberculosis Patients.

14:50-15:10       Sofie Dhaese (Universiteit Gent)

Translating evidence from preclinical infection models to clinically relevant dosing targets of beta-lactam antibiotics in critically ill patients.

15:10-15:50       Coffee break

15:50-16:15       Sebastiaan Goulooze (LACDR, Leiden)

Novel pharmacometric techniques to quantify and prevent iatrogenic withdrawal in children.

16:15-16:40       Feifan Xie (Universiteit Gent)

Use of PKPD modelling for the treatment optimization in ovarian cancer patients treated with cisplatin-based intraoperative intraperitoneal chemotherapy.

16:40-17:05       Erwin Dreesen & Wannee Kantasiripitak (KU Leuven)

Pharmacometric models to improve therapeutic drug monitoring of monoclonal antibodies in the treatment of inflammatory bowel diseases.

17:05-17:30       Gilbert Koch (University of Basel, Children’s Hospital)

OptiDose: An advanced approach to compute optimal drug dosing schemes for a PKPD model using optimal control theory.

17:30-18:30 Closure and drinks