Vergadercentrum De Stroming, Antwerpen, Belgium on Thursday April 20th, 2023
Program
12.00 – 13.00 Walk-in and lunch
13.00 – 13.10 Welcome by PNB steering committee
13.10 – 13.35 Babies are not small adults, but are preterm neonates just smaller babies? Raltegravir dosing in preterm neonates. Jos Lommerse, Certara (NL)
13.35 – 14.00 Combining ex vivo human placenta perfusion data with PBPK models to estimate fetal drug exposure. Hedwig van Hove, Radboud UMC (NL)
14.00 – 14.25 Model Informed Dose Selection for Aticaprant in Adolescent Patients. Xia Li , Janssen Research & Development (BE)
14.25 – 14.50 PBPK modeling of UGT1A1, -1A4, and -2B7 cleared drugs in pregnant women. Ymke van der Velde, Rijksuniversiteit Groningen (NL)
14.50 – 15.20 Coffee break
15.20 – 15.45 PBPK modelling to predict local lung exposure of meropenem in people with cystic fibrosis. Pieter-Jan De Sutter, Universiteit Gent (BE)
15.45 – 16.10 Amikacin Dose Optimization in the Emergency Department: a Population Pharmacokinetic Simulation Study. Nada Dia, KU Leuven (BE)
16.10 – 16.35 Exploring the impact of obesity on drug clearance using PBPK modelling approaches: influential variables affecting scaling from non-obese to obese subjects for drugs metabolized in the liver. Tan Zhang, Leiden Academic Centre for Drug Research (NL)
16.35 – 17.00 Drug model specialization: The right model for the job?. Douglas Eleveld, University Medical Center Groningen (NL)
17.00 – 18.00 Drinks